Hope Never Dies

by Rick Shapiro

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  • Many Paths to Wellness – 2023 CAM for Cancer Conference
  • Finding Your Best Anti-Cancer Nutrition Plan
  • Fasting to Mitigate Chemo Side-Effects
  • Curcumin: A Powerful Anti-Cancer Agent
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Curcumin: A Powerful Anti-Cancer Agent

February 25, 2021 by Rick Shapiro Leave a Comment

Curcumin Anti-Cancer Agent Hope Never Dies BlogCurcumin is a component of the spice turmeric, which can be found in many people’s spice cabinets. Commonly consumed in many Asian countries as a culinary ingredient, it gives curry and mustard their yellow color. Turmeric has also been used for medicinal purposes for centuries.

Curcumin is the biologically active agent in turmeric. Approximately 2% to 5% of turmeric is composed of Curcumin. Many studies and clinical evidence confirm that curcumin delivers myriad benefits to cancer patients. One of its primary proven benefits is its anti-inflammatory effect.

Inflammation fighter

An abundance of evidence from numerous studies (preclinical, animal and clinical) strongly suggest curcumin exerts potent anti-cancer and anti-inflammatory activities.

It is well-known that chronic inflammation is an underlying problem and driver of many diseases, including cancer. And, cancer further drives and spreads internal-chronic inflammation. The NF-kB (nuclear factor kappa beta) protein, a proinflammatory signaling pathway (aka – transcription factor), is essentially the “master-switch” for inflammation. It is one of the most important molecules linking chronic inflammation to cancer problems, including cell proliferation, angiogenesis, tumor promotion and metastasis.

Inhibiting and suppressing NF-kB signaling is a therapeutic objective when fighting cancer, and the natural agent curcumin has been shown to be effective in achieving this goal. An abundance of evidence from numerous studies (preclinical, animal and clinical) strongly suggest curcumin exerts potent anti-cancer and anti-inflammatory activities. In addition to its role in fighting cancer, curcumin plays a multifaceted role in cancer prevention. Due to its many anti-inflammatory benefits, it also delivers a cascade of other benefits for other inflammatory conditions, including arthritis.

Personally (and not for cancer reasons), I have found curcumin to be very effective, and I incorporate it into my daily supplementation regimen to alleviate sundry aches and pains, by mitigating that gnarly instigator: inflammation. For me, it works wonders!

Curcumin dosage and interactions

Dosage always matters, whether a patient is using pharmaceutical drugs or evidence-based supplements. Thus, an individual patient’s issues will dictate appropriate dosing. Curcumin has been used, up to 12 grams per day, for up to three months without any significant side-effects, although most cancer patients take a lesser amount of approximately 3.0 to 8.0 grams per day, for longer time periods.

Also, drug interactions need to be assessed with any supplement or pharmaceutical agent. It has been suggested that curcumin may have an anticoagulant effect, thus if a patient is already taking anticoagulant agents (such as blood thinners), caution would be advised.

Absorption

One challenge with curcumin is the notion that it is not bioavailable — in other words, it doesn’t absorb well into one’s system. Thus, it is advisable to take curcumin (if a capsule or tablet) with bioperine or piperine (derived from black pepper) which, purportedly, helps enhance absorption. Many curcumin supplements include this component in their ingredients.

Of course, effective cancer protocols require a sophisticated multifaceted approach. I strongly recommend you explore curcumin as a strong anti-inflammatory agent, to be included in the toolbox of comprehensive and effective interventions.

Finally, prior to embarking on any medical or healthcare protocol, intervention or regimen, always seek the counsel of a qualified doctor or healthcare professional.

Learn more about curcumin, and the power of other integrative therapies, in my book, Hope Never Dies.

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Filed Under: Blog, Botanicals, Inflammation, Nutrition Tagged With: anti-inflammatory, curcumin, diet, food, medicine, metastatic

Can Food Choices Influence the Prevention and Progression of Cancer

June 29, 2017 by Rick Shapiro Leave a Comment

To decrease cancer risk, select fruit like blueberries that have anti-oxidant and anti-inflammatory properties.

Can food choices influence the prevention and progression of cancer? 

SHORT ANSWER: ABSOLUTELY YES. This is a deep and exhaustive cancer subject and has been a topic of debate for centuries. The so-called “Father of Modern Medicine” Hippocrates, born approximately 2,500 years ago, is well known for his famous quote:

Let Food Be Thy Medicine and Let Medicine Be Thy Food

His prescient understanding of how food impacts our health was remarkable, given the lack of analytical testing mechanisms (blood work and other medical-diagnostic tools) at his disposal. He was at the forefront of in-depth clinical observation and documentation. Today, an abundance of evidence strongly suggests that the inclusion of certain foods and the exclusion of other foods can have a major effect upon cancer. I will keep this article brief and expand upon it in future articles, but provide you, herein, with some “food for thought.”

Jeanne Wallace, Ph.D. 

Jeanne wrote a compelling chapter in Hope Never Dies. She is a world-renowned specialist in the dietary and nutritional cancer world.

In speaking with Jeanne, I pointed out that there are many so-called anti-cancer diets, including the gluten-free, macrobiotic, Gerson, Ludwig, ketogenic, paleo, raw, vegan, vegetarian, and other diets. She takes a non-dogmatic approach:

“There are advantages and disadvantages to each of these diet approaches. While some of our clients might thrive on a vegetarian diet, others will be healthier eating some humanely raised, pasture-fed/finished meat. While a Gerson-type diet (organic plant-based) will provide ample phytonutrients for modifying gene expression, it can be disastrous to one’s blood sugar control.

Ditto macrobiotic approaches, which can be very healing for individuals whose genetic predisposition suits them to such an eating plan, but will worsen insulin resistance in others. A raw foods diet often works well as a short-term intervention to increase one’s connectedness to food vibrancy, but carotenoids and other flavonoids have low bioavailability in their raw state and are optimized when cooked and eaten with healthy fats.”

Jeanne and her staff engage in global translational research. They educate and counsel clients (and doctors) about evidence-based nutrition, which is tailored to patients based upon numerous factors. These factors comprise an individual’s biochemical criteria, including a client’s specific cancer type, stage and other related issues.

Jeanne also asserts:

A diet that fosters systemic inflammation, insulin resistance, excess blood viscosity, nutrient imbalances and immune suppression will have a permissive effect with malignant cells. So, contrarily, our primary goal is to lessen these factors and create an internal environment that is not conducive to cancer growth and progression. Most exciting is the discovery that our diet has direct effects on cancer genes.

We’ve learned that genes are more plastic than originally thought. Gene expression is not written in stone; we’re not stuck with the genetic luck-of-the-draw with which we’re born. While we can’t change the actual gene, we do have significant influence over which genes are expressed and which are kept dormant. Research in nutritional epigenetics is revealing how—at the molecular and genetic level—various anti-cancer foods repress the expression of oncogenes (genes that foster the growth and promotion of cancer) and up-regulate the expression of tumor suppressor genes.

Keith Block, M.D. 

Dr. Keith Block is a world-renowned integrative cancer doctor. He has also written a compelling chapter in Hope Never Dies.
He states:

Regarding the impact of diet, it is clear that the typical Western diet can drive the onset of malignancy. For example, according to several studies, red meat can increase the risk of colorectal cancer by 25 to 75 percent. Also, high milk and calcium consumption are associated with a 15 to 200 percent increase in prostate cancer. And one randomized controlled trial showed that when breast cancer patients reduced their fat intake to 20 percent or lower, they reduced their risk of recurrence by an average of 24 percent! This is on par with Tamoxifen, which has shown a 25 percent reduction in recurrence rates after taking it for five years.

Another example: 25 grams of flax per day will cut your Ki67, a proliferation marker for cancer, by 34 percent. There is also evidence to suggest that 25 grams of flaxseed per day can induce apoptosis (the normal, genetically-regulated process of cell death) by 30 percent.

Yet, we don’t talk about nutrition specificity as medical culture. There is also impressive data showing that if you shift to a whole grain, legume-based, vegetable and fruit diet, you cut back cancer risks dramatically, yet there is less than a three percent chance that your cancer specialist will bring up a discussion about diet with you!

Keith treats his patients with a multi-interventional, systemic and comprehensive integrative regimen, based upon objective diagnostic criteria tailored to the individual, and not based upon the strict “standard of care,” alone.

What are the best foods to eat to avoid cancer?

I’m often asked for lists of what to eat and avoid. There is no perfect list of anti-cancer foods because everyone is an individual with different needs, but there are some common sense choices, based upon numerous research studies that certain foods and food categories should be avoided and, on the contrary, others included.

Anti-cancer food suggestions from Jeanne Wallace, Ph.D.

  • Cruciferous vegetables (including broccoli, cabbage, cauliflower, kale, collards, brussel sprouts, radishes, and mustard)
  • Carotenoid-rich fruits and vegetables (known for their deep orange, red and yellow hues)
  • Leafy greens
  • Berries
  • Spices
  • Green tea

Foods generally deemed deleterious to cancer prevention

  • Refined, processed and packaged foods with excessive sugar
  • GMOs and artificial ingredients
  • Pesticide or hormone-laden factory-farm-raised meats/poultry/dairy/eggs
  • Preserved meats and fish with nitrates
  • Soft drinks and alcoholic beverages
  • Refined vegetable oils
  • Hydrogenated and trans fats

Intelligent food choices that are adhered to and implemented every day can play a major role in preventing cancer and impacting its progression.

Be aware of what you eat at every meal and understand that food or food products can have a direct effect on your body, especially if you have been diagnosed with cancer and are attempting to thwart its progression or keep it in remission.

Have a Wonderful Healthy Day and Keep the Hope!

Rick Shapiro, Author 

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What is the Difference Between Conventional, Integrative, and Alternative Cancer Care?

March 20, 2017 by Rick Shapiro Leave a Comment

Differences between conventional, alternative, and integrative therapies. Hope Never Dies

In today’s world, the standard of care is generally defined as: surgery, chemotherapy, and radiation.

Conventional Cancer Therapies

Most conventional cancer therapies, which are prescribed and directed by mainstream doctors, are comprised of what is known as the “standard of care.” In today’s world, the standard of care is generally defined as: surgery, chemotherapy, and radiation. These are the primary modalities used in conventional cancer therapy, however, there are others, including hormonal and, more recently, novel immunotherapies. We are at the dawn of the immunotherapeutic age and this is not a perfected therapy, but there appears to be new hope and progress in this treatment realm. In fact, there is “no perfect therapy” for all cancers and cancer patients. But, there are many therapeutic paths that can provide great benefit, and that includes therapies that “are not” strictly standard of care therapies.

Integrative Cancer Therapies

Integrative cancer therapy combines therapies from both the widely recognized, mainstream standard of care world, which is conventional medicine, and non-standard of care medicine, which is frequently called alternative or complementary medicine which “complements” the conventional therapies. Therefore, we have conventional and alternative therapies combined, working simultaneously, thus they are working integratively. The goal of integrative medicine is for the doctors and/or respective medical teams to bring the best of both worlds together.

Alternative Cancer Therapies

Alternative cancer therapy is comprised of individual treatments or multi-faceted therapeutic regimens which do not include conventional cancer therapy. Hundreds of types of treatments are known as alternative cancer therapy. As an example, more well-known, supportive alternative therapies may include: various focused-nutritional strategies, different kinds of exercise regimens, a variety of mind-body protocols, and prescribed supplementation – which may include certain types of vitamins, botanicals and/or other extracts. Again, there are many other types of alternative treatments and therapies. Some are supported by strong evidence of efficacy and safety, others are of questionable value.

There are millions of people who have beaten cancer and transformed their health by implementing one (or a combination) of the three approaches, above, in their encounter with early-stage cancer, late-stage cancer, and cancer patients who have been given terminal cancer prognoses (see – Hope Never Dies – for 20 compelling stories).

 

Have a Wonderful Healthy Day and Keep the Hope!

Rick Shapiro, Author 

 

 

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